Flexible service offerings
If you have your own choice of ES cell handling and animal facility,
i.e. some academic institutions have their own gene targeting
facilities, you can choose either service 1 or 2 to complement
the services offered by the facility. On your behalf, we can help
consult the whole experiment process to relieve you from the tedious
technical details and communications involved in a gene targeting
project.
Service 1: BAC library screening
For clients who want to construct knock-out vectors starting from
a BAC clone, we can screen BAC library and isolate the BAC clone
containing your gene of interest. Project duration is usually
less than 3 weeks.
Service 2: Construction of
targeting vector
We advise clients on targeting strategy and the screening strategy
that follows. We design and construct targeting vectors for both
conventional knock-outs and conditional knock-outs based on client's
specifications. Project duration is usually less than 2 months.
Service 3: Electroporation, selection, and expansion (Provided
by third party)
If you do not have a gene targeting facility in mind, we can recommend
several qualified academic core facilities, which charge affordable
prices. A proper facility is selected based on facility wait-time
and other considerations.
Service 4: Blastocyst injection, chimera breeding and germline
transmission (Provided by third party)
If you do not have a facility in mind, we can recommend several
qualified academic core facilities, which charge affordable prices. A proper facility is selected based on facility wait-time
and other considerations.
service
inquiry/request
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