Flexible service offerings

If you have your own choice of ES cell handling and animal facility, i.e. some academic institutions have their own gene targeting facilities, you can choose either service 1 or 2 to complement the services offered by the facility. On your behalf, we can help consult the whole experiment process to relieve you from the tedious technical details and communications involved in a gene targeting project.

Service 1: BAC library screening
For clients who want to construct knock-out vectors starting from a BAC clone, we can screen BAC library and isolate the BAC clone containing your gene of interest. Project duration is usually less than 3 weeks.

Service 2: Construction of targeting vector
We advise clients on targeting strategy and the screening strategy that follows. We design and construct targeting vectors for both conventional knock-outs and conditional knock-outs based on client's specifications. Project duration is usually less than 2 months.

Service 3: Electroporation, selection, and expansion (Provided by third party)
If you do not have a gene targeting facility in mind, we can recommend several qualified academic core facilities, which charge affordable prices. A proper facility is selected based on facility wait-time and other considerations.

Service 4: Blastocyst injection, chimera breeding and germline transmission (Provided by third party)
If you do not have a facility in mind, we can recommend several qualified academic core facilities, which charge affordable prices. A proper facility is selected based on facility wait-time and other considerations.